Lange, Klaus W. (1989) Modification by apomorphine of the circling behaviour in the rat due to unilateral intranigral injection of 1-methyl-4-phenylpyridine (MPP+). Journal de toxicologie clinique et expérimentale 9 (1), pp. 21-25.
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Abstract
Unilateral injection of MPP+ (4 micrograms/1 microliter) into the pars compacta of the substantia nigra in rats induced ipsiversive circling immediately after the injection. Ipsiversive circling was still present 7 days after the injection. Systemic injection of the dopamine agonist apomorphine induced contraversive circling. These results show that MPP+ exerts a powerful neurotoxic action on the ...
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| Item type: | Article | ||||||||||||||||||||
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| Date: | 1989 | ||||||||||||||||||||
| Institutions: | Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange | ||||||||||||||||||||
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| Dewey Decimal Classification: | 100 Philosophy & psychology > 150 Psychology | ||||||||||||||||||||
| Status: | Published | ||||||||||||||||||||
| Refereed: | Yes, this version has been refereed | ||||||||||||||||||||
| Created at the University of Regensburg: | Unknown | ||||||||||||||||||||
| Item ID: | 25448 |
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