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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-254491
- DOI to cite this document:
- 10.5283/epub.25449
Abstract
(+)-4-Propyl-9-hydroxynaphthoxazine (+PHNO) is a potent dopamine agonist that has been administered transdermally to four patients with Parkinson's disease and "on-off" fluctuations. Skin patches of increasing size were used to treat these patients, who also received infrequent doses of oral levodopa if required. The effect of +PHNO was measured as an increased duration of action of individual ...

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