Coleman, R. J., Lange, Klaus W., Quinn, N. P., Loper, A. E., Bondi, J. V., Hichens, M., Stahl, S. M. und Marsden, C. D.
The antiparkinsonian actions and pharmacokinetics of transdermal (+)-4-propyl-9-hydroxynaphthoxazine (+PHNO): preliminary results.
Movement disorders 4 (2), S. 129-138.
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(+)-4-Propyl-9-hydroxynaphthoxazine (+PHNO) is a potent dopamine agonist that has been administered transdermally to four patients with Parkinson's disease and "on-off" fluctuations. Skin patches of increasing size were used to treat these patients, who also received infrequent doses of oral levodopa if required. The effect of +PHNO was measured as an increased duration of action of individual ...
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