Go to content
UR Home

The antiparkinsonian actions and pharmacokinetics of transdermal (+)-4-propyl-9-hydroxynaphthoxazine (+PHNO): preliminary results

Coleman, R. J., Lange, Klaus W., Quinn, N. P., Loper, A. E., Bondi, J. V., Hichens, M., Stahl, S. M. and Marsden, C. D. (1989) The antiparkinsonian actions and pharmacokinetics of transdermal (+)-4-propyl-9-hydroxynaphthoxazine (+PHNO): preliminary results. Movement disorders 4 (2), pp. 129-138.

[img]
Preview
PDF
Download (473kB)
Date of publication of this fulltext: 20 Jul 2012 13:25

at PubMed

at publisher (via DOI)


Abstract

(+)-4-Propyl-9-hydroxynaphthoxazine (+PHNO) is a potent dopamine agonist that has been administered transdermally to four patients with Parkinson's disease and "on-off" fluctuations. Skin patches of increasing size were used to treat these patients, who also received infrequent doses of oral levodopa if required. The effect of +PHNO was measured as an increased duration of action of individual ...

plus


Export bibliographical data



Item type:Article
Date:1989
Institutions:Psychology and Pedagogy > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange
Identification Number:
ValueType
2733705PubMed ID
10.1002/mds.870040204DOI
Classification:
NotationType
Administration, CutaneousMESH
AdultMESH
Antiparkinson Agents/pharmacokineticsMESH
Dopamine AntagonistsMESH
Drug Administration ScheduleMESH
Drug Therapy, CombinationMESH
HumansMESH
Levodopa/administration & dosageMESH
Middle AgedMESH
Motor Skills/drug effectsMESH
Oxazines/pharmacokineticsMESH
Parkinson Disease/drug therapyMESH
Dewey Decimal Classification:100 Philosophy & psychology > 150 Psychology
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:25449
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons