| License: Creative Commons: Attribution 3.0 PDF - Published Version (259kB) |
- URN to cite this document:
- urn:nbn:de:bvb:355-epub-258626
- DOI to cite this document:
- 10.5283/epub.25862
Alternative links to fulltext:DOI
Abstract
Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians. Besides age and smoking, genetic variants from several gene loci have reproducibly been associated with this condition and likely explain a large proportion of disease. Here, we developed a genetic risk score (GRS) for AMD based on 13 risk ...

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