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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-260810
- DOI to cite this document:
- 10.5283/epub.26081
Abstract
Myeloid-derived suppressor cells (MDSCs) are natural immunosuppressive cells and endogenous inhibitors of the immune system. We describe a simple and clinically-compatible method of generating large numbers of MDSCs, using the cultures of peripheral blood-isolated monocytes supplemented with prostaglandin E2 (PGE2). We observed that PGE2 induces endogenous COX2 expression in cultured monocytes, ...
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