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Neoimmun versus Neoral: a bioequivalence study in healthy volunteers and influence of a fat-rich meal on the bioavailability of Neoimmun

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Kees, F. ; Bucher, M. ; Schweda, F. ; Gschaidmeier, H. ; Faerber, L. ; Seifert, R.
Date of publication of this fulltext: 05 Aug 2009 13:40


In two crossover studies with 12 (6 males/6 females) healthy young volunteers each, we compared the bioavailability of Neoimmun capsules with the microemulsion Neoral and the influence of a fat-rich breakfast on the bioavailability of Neoimmun. Each volunteer received a single dose of 200 mg cyclosporine A in each period. Blood samples were taken up to 24 h and analysed for cyclosporine A by ...


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