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Oxygen-dependent erythropoietin production by the isolated perfused rat kidney

Scholz, Holger, Schurek, H. J., Eckardt, Kai-Uwe, Kurtz, Armin and Bauer, Christian (1991) Oxygen-dependent erythropoietin production by the isolated perfused rat kidney. Pflügers Archiv : European journal of physiology 418 (3), pp. 228-233.

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Abstract

In this study we have investigated the role of oxygen delivery and of classic second messengers on erythropoietin production by the isolated perfused rat kidney. We found that the rat kidney was capable of de novo synthesis of erythropoietin. The erythropoietin production rate was inversely related to the oxygen pressure in the perfusate and increased from 0.17 to 1.85 U erythropoietin h-1 g ...

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Item type:Article
Date:1991
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
1649989PubMed ID
Classification:
NotationType
AnimalsMESH
Calmodulin/antagonists & inhibitorsMESH
Cyclic GMP/pharmacologyMESH
Erythropoietin/biosynthesisMESH
Forskolin/pharmacologyMESH
Imidazoles/pharmacologyMESH
Kidney/metabolismMESH
KineticsMESH
MaleMESH
Oxygen/pharmacologyMESH
RatsMESH
Second Messenger SystemsMESH
Sulfonamides/pharmacologyMESH
Vascular Resistance/drug effectsMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26962
Owner only: item control page

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