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Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure

Kindler, J., Eckardt, Kai-Uwe, Ehmer, B., Jandeleit, K., Kurtz, Armin, Schreiber, A., Scigalla, P. and Sieberth, H. G. (1989) Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure. Nephrology, dialysis, transplantation 4 (5), pp. 345-349.

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Abstract

The pharmacokinetic profile of recombinant human erythropoietin (rHuEpo) was studied after a single intravenous dose of 150 U/kg in ten patients with various degrees of renal function: group I, creatinine clearance greater than 80 ml/min, n = 2; group II, creatinine clearance 10-50 ml/min, n = 6; group III, creatinine clearance less than 3 ml/min (patients undergoing haemodialysis) n = 2. ...

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Item type:Article
Date:1989
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
2505184PubMed ID
Classification:
NotationType
AdultMESH
AgedMESH
Dose-Response Relationship, DrugMESH
Erythropoietin/pharmacokineticsMESH
FemaleMESH
Glomerular Filtration RateMESH
HumansMESH
Injections, IntravenousMESH
Kidney Failure, Chronic/therapyMESH
Kidney Function TestsMESH
MaleMESH
Middle AgedMESH
Recombinant Proteins/pharmacokineticsMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26987
Owner only: item control page

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