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Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure

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Kindler, J. ; Eckardt, Kai-Uwe ; Ehmer, B. ; Jandeleit, K. ; Kurtz, Armin ; Schreiber, A. ; Scigalla, P. ; Sieberth, H. G.
Date of publication of this fulltext: 20 Dec 2012 14:32


The pharmacokinetic profile of recombinant human erythropoietin (rHuEpo) was studied after a single intravenous dose of 150 U/kg in ten patients with various degrees of renal function: group I, creatinine clearance greater than 80 ml/min, n = 2; group II, creatinine clearance 10-50 ml/min, n = 6; group III, creatinine clearance less than 3 ml/min (patients undergoing haemodialysis) n = 2. ...


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