Adenosine stimulates guanylate cyclase activity in vascular smooth muscle cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-270006
DOI to cite this document:: 10.5283/epub.27000

Kurtz, Armin

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Date of publication of this fulltext: 08 Jan 2013 08:23

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Abstract

Good evidence exists to indicate that the vasodilating effect of adenosine is mediated by cell surface receptors on vascular smooth muscle cells. The mechanism of transmembrane signal transduction for adenosine, however, is not fully understood. Since cGMP is a second messenger known to mediate vasodilation, I have examined the effect of adenosine on the intracellular concentration of cGMP in ...