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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-270056
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.27005
Zusammenfassung
We have examined the effect of a synthetic analogue of human alpha-atrial natriuretic peptide (ANP), APII, on renin release in cultured renal juxtaglomerular cells (JGA cells). Using cell cultures containing 80-90% renal juxtaglomerular cells, we found that ANP (10(-13)-10(-9) M) strongly inhibited renin release from the cells in a dose-dependent fashion (ki, 10 pM) to about 10% of control. ...
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