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Role of protein kinase C in inhibition of renin release caused by vasoconstrictors

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Kurtz, Armin ; Pfeilschifter, J. ; Hutter, A. ; Bührle, C. ; Nobiling, R. ; Taugner, R. ; Hackenthal, E. ; Bauer, C.
Date of publication of this fulltext: 05 Dec 2012 10:29


It was the aim of the present study to get insight into some of the intracellular mechanisms by which the vasoconstrictor hormones angiotensin II (ANG II), arginine vasopressin (AVP), and norepinephrine (NE) inhibit renin release from renal juxtaglomerular cells. To this end a primary cell culture from rat renal cortex was established that consisted of 50% juxtaglomerular cells. The cultured ...


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