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Targeting drugs to mitochondria

Heller, Anne ; Brockhoff, Gero ; Goepferich, Achim



Abstract

Mitochondria are of an increasing interest in pharmaceutical and medical research since it has been reported that dysfunction of these organelles contributes to several diseases with a great diversity of clinical appearance. By the fact that mitochondria are located inside the cell and, in turn, origins of mitochondrial diseases or targets of drugs are located inside mitochondria, a drug molecule ...

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