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Characterisation of the Rrp5p/Noc1p/Noc2p protein complex and its function in ribosome biogenesis of Saccharomyces cerevisiae

Hierlmeier, Thomas (2013) Characterisation of the Rrp5p/Noc1p/Noc2p protein complex and its function in ribosome biogenesis of Saccharomyces cerevisiae. PhD, Universität Regensburg.

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Date of publication of this fulltext: 12 Apr 2013 14:04

Abstract (English)

Eukaryotic ribosome biogenesis is a very complex process that includes synthesis of the structural components (ribosomal RNAs (rRNAs) and proteins (r-proteins)), processing and folding of rRNA precursors, as well as assembly of the r-proteins onto the rRNA. Ribosome biogenesis starts with the transcription of the genes encoding the rRNAs (rDNA) in the nucleolus by RNA polymerase I and III, and ...

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Translation of the abstract (German)

Die eukaryotische Ribosomenbiogenese ist ein hochkomplexer Prozess, der die Synthese der strukturellen Komponenten (ribosomale RNAs (rRNAs) und Proteine (r-Proteine)), Prozessierung und Faltung der rRNA Vorläufer, sowie die Assemblierung der r-Proteine auf der rRNA beinhaltet. Die Ribosomenbiogenese beginnt in einem spezialisierten Teil des Zellkerns, dem Nukleolus, mit der von den RNA ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:15 January 2013
Referee:Prof. Dr. Herbert Tschochner and Prof. Dr. Gunter Meister and Prof. Dr. Klaus Grasser
Date of exam:1 March 2013
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Herbert Tschochner
Interdisciplinary Subject Network:Not selected
Keywords:ribosome synthesis, RNA polymerase I, ribonucleoprotein complex RNP, SSU processome, large ribosomal subunit, rDNA chromatin, co-transcriptional assembly
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28040
Owner only: item control page

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