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Photodynamic inactivation of microbial biofilms: impact of Hsp70 expression and non-invasive optical monitoring of oxygen during photodynamic inactivation

Pereira Gonzales, Fernanda (2013) Photodynamic inactivation of microbial biofilms: impact of Hsp70 expression and non-invasive optical monitoring of oxygen during photodynamic inactivation. PhD, Universität Regensburg.

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Date of publication of this fulltext: 05 Aug 2013 13:36

Abstract (English)

Candida albicans is the main type of fungi able to form biofilms, which cause superficial skin and mucous membrane infections as well as invasive mycoses, particularly in immunocompromised patients. In these patients, invasive infections are often associated with high morbidity and mortality. Furthermore, the increase in antifungal resistance has decreased the efficacy of conventional therapies. ...

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Translation of the abstract (German)

Candida albicans ist die wichtigste Pilzart, welche fähig ist, Biofilme zu bilden. Sie verursachen vor allem bei immunsupprimierten Patienten oberflächliche Haut- und Schleimhautentzündungen sowie invasive Mykosen. Bei solchen Patienten werden invasive Infektionen oft mit einer erhöhten Morbidität und Mortalität in Verbindung gebracht. Zudem hat die verstärkte antimykotische Resistenz die ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:5 August 2013
Referee:Prof. Dr. Otto S. Wolfbeis
Date of exam:8 May 2013
Institutions:Medicine > Lehrstuhl für Dermatologie und Venerologie
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie
Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Keywords:Photodynamic, Candida albicans, biofilm, singlet oxygen, Singulett-Sauerstoff
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28548
Owner only: item control page

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