Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

URN to cite this document:: urn:nbn:de:bvb:355-epub-287820
DOI to cite this document:: 10.5283/epub.28782

Randall, Joshua C. ; Winkler, Thomas W. ; Heid, Iris M.

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Date of publication of this fulltext: 03 Sep 2013 09:47

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Abstract

Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip circumference, and waist-to-hip-ratio (133,723 individuals) and took forward 348 SNPs into follow-up (additional 137,052 individuals) in a total of ...