Ramm Sander, Paul, Peer, Markus, Grandl, Margot, Bogdahn, Ulrich, Schmitz, Gerd and Kalbitzer, Hans Robert (2013) NMR spectroscopy of macrophages loaded with native, oxidized or enzymatically degraded lipoproteins. PloS one 8 (2), e56360.
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Abstract
Oxidized and enzymatically modified low-density lipoproteins (oxLDL and eLDL) play a key role in early stages of atherogenesis. Their uptake by recruited macrophages leads to endolysosomal phospholipidosis or foam cell formation, respectively, each of which is preceded by highly differential lipid restructuring processes. We applied (1)H-NMR spectroscopy (NMRS) to elucidate these structural ...
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| Item type: | Article | ||||||||||||||||
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| Date: | 2013 | ||||||||||||||||
| Institutions: | Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer | ||||||||||||||||
| Projects: | Open Access Publizieren (DFG) | ||||||||||||||||
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| Dewey Decimal Classification: | 500 Science > 570 Life sciences | ||||||||||||||||
| Status: | Published | ||||||||||||||||
| Refereed: | Yes, this version has been refereed | ||||||||||||||||
| Created at the University of Regensburg: | Yes | ||||||||||||||||
| Item ID: | 28815 |
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