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Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy

Kern, K., Schebesch, Karl-Michael, Schlaier, J., Hansen, Ernil, Feigl, Guenther C., Brawanski, Alexander and Lange, M. (2012) Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 19 (1), pp. 99-100.

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Abstract

Anticonvulsant drugs are frequently given after craniotomy. Phenytoin (PHT) is the most commonly used agent; levetiracetam (LEV) is a new anticonvulsant drug with fewer side effects. To compare the incidence of seizures in patients receiving either prophylactic PHT or LEV perioperatively, 971 patients undergoing a craniotomy were analysed retrospectively during a 2-year period. PHT was used ...

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Item type:Article
Date:2012
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
22133815PubMed ID
10.1016/j.jocn.2011.07.021DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Aged, 80 and overMESH
Brain Neoplasms/surgeryMESH
ChildMESH
Craniotomy/methodsMESH
FemaleMESH
HumansMESH
MaleMESH
Middle AgedMESH
Phenytoin/therapeutic useMESH
Piracetam/therapeutic useMESH
Postoperative Complications/prevention & controlMESH
Retrospective StudiesMESH
Seizures/prevention & controlMESH
Young AdultMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29170
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