Go to content
UR Home

Expression of carbonic anhydrase IX in craniopharyngiomas

Proescholdt, Martin A. ; Merrill, Marsha ; Stoerr, Eva-Maria ; Lohmeier, Annette ; Dietmaier, Wolfgang ; Brawanski, Alexander



Abstract

Carbonic anhydrase IX, which is virtually absent in normal brain, is significantly upregulated in craniopharyngiomas and shows a significant association with cyst size. The mechanisms of regulation remain unknown, since neither hypoxia nor p53 appears to play a role. These results indicate that inhibition of CA IX may be a potential target for the adjuvant treatment in patients with cystic craniopharyngiomas.


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons