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Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group

Stupp, R., Tosoni, A., Bromberg, J. E. C., Hau, Peter, Campone, M., Gijtenbeek, J., Frenay, M., Breimer, L., Wiesinger, H., Allgeier, A., van den Bent, M. J., Bogdahn, Ulrich, van der Graaf, W., Yun, H. J., Gorlia, T., Lacombe, D. and Brandes, A. A. (2011) Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 22 (9), pp. 2144-2149.

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Abstract

No evidence of relevant clinical antitumor activity against recurrent glioblastoma could be detected. Sagopilone was well tolerated, and moderate-to-severe peripheral neuropathy was observed in despite prolonged administration.


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Item type:Article
Date:2011
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
20159801PubMed ID
10.1093/annonc/mdq729DOI
Classification:
NotationType
AdultMESH
AgedMESH
Antineoplastic Agents/therapeutic useMESH
Astrocytoma/drug therapyMESH
Benzothiazoles/therapeutic useMESH
Brain Neoplasms/drug therapyMESH
Disease ProgressionMESH
Disease-Free SurvivalMESH
Epothilones/therapeutic useMESH
FemaleMESH
Glioblastoma/drug therapyMESH
HumansMESH
Infusions, IntravenousMESH
MaleMESH
Middle AgedMESH
Neoplasm Recurrence, Local/drug therapyMESH
Young AdultMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29189
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