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Transcranial electro-hyperthermia combined with alkylating chemotherapy in patients with relapsed high-grade gliomas: phase I clinical results

Wismeth, Caecilia, Dudel, Christine, Pascher, Christina, Ramm, Paul, Pietsch, Torsten, Hirschmann, Birgit, Reinert, Christiane, Proescholdt, Martin A., Rümmele, Petra, Schuierer, Gerhard, Bogdahn, Ulrich and Hau, Peter (2010) Transcranial electro-hyperthermia combined with alkylating chemotherapy in patients with relapsed high-grade gliomas: phase I clinical results. Journal of neuro-oncology 98 (3), pp. 395-405.

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Abstract

Non-invasive loco-regional electro-hyperthermia (EHT) plus alkylating chemotherapy is occasionally used as salvage treatment in the relapse of patients with high-grade gliomas. Experimental data and retrospective studies suggest potential effects. However, no prospective clinical results are available. We performed a single-center prospective non-controlled single-arm Phase I trial. Main ...

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Item type:Article
Date:2010
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
20033471PubMed ID
10.1007/s11060-009-0093-0DOI
Classification:
NotationType
AgedMESH
Antineoplastic Agents, Alkylating/therapeutic useMESH
Brain Neoplasms/therapyMESH
Combined Modality Therapy/methodsMESH
FemaleMESH
Glioma/therapyMESH
HumansMESH
Hyperthermia, Induced/methodsMESH
Magnetic Resonance Imaging/methodsMESH
MaleMESH
Middle AgedMESH
Prospective StudiesMESH
RecurrenceMESH
Severity of Illness IndexMESH
Treatment OutcomeMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29208
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