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O-(2-[18F]fluoroethyl)-L-tyrosine PET combined with MRI improves the diagnostic assessment of cerebral gliomas

Pauleit, Dirk, Floeth, Frank, Hamacher, Kurt, Riemenschneider, Markus J., Reifenberger, Guido, Müller, Hans-Wilhelm, Zilles, Karl, Coenen, Heinz H. and Langen, Karl-Josef (2005) O-(2-[18F]fluoroethyl)-L-tyrosine PET combined with MRI improves the diagnostic assessment of cerebral gliomas. Brain : a journal of neurology 128 (Pt. 3), pp. 678-687.

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Abstract

MRI is commonly used to determine the location and extent of cerebral gliomas. We investigated whether the diagnostic accuracy of MRI could be improved by the additional use of PET with the amino acid O-(2-[18F]fluoroethyl)-l-tyrosine (FET). In a prospective study, PET with FET and MRI was performed in 31 patients with suspected cerebral gliomas. PET and MRIs were co-registered and 52 ...

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Item type:Article
Date:2005
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
15689365PubMed ID
10.1093/brain/awh399DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
BiopsyMESH
Brain Neoplasms/radionuclide imagingMESH
ChildMESH
Child, PreschoolMESH
FemaleMESH
Fluorine Radioisotopes/diagnostic useMESH
Glioma/radionuclide imagingMESH
HumansMESH
Magnetic Resonance ImagingMESH
MaleMESH
Middle AgedMESH
Positron-Emission Tomography/methodsMESH
Prospective StudiesMESH
Sensitivity and SpecificityMESH
Tyrosine/diagnostic useMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29251
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