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O-(2-[18F]fluoroethyl)-L-tyrosine PET combined with MRI improves the diagnostic assessment of cerebral gliomas

Pauleit, Dirk ; Floeth, Frank ; Hamacher, Kurt ; Riemenschneider, Markus J. ; Reifenberger, Guido ; Müller, Hans-Wilhelm ; Zilles, Karl ; Coenen, Heinz H. ; Langen, Karl-Josef


MRI is commonly used to determine the location and extent of cerebral gliomas. We investigated whether the diagnostic accuracy of MRI could be improved by the additional use of PET with the amino acid O-(2-[18F]fluoroethyl)-l-tyrosine (FET). In a prospective study, PET with FET and MRI was performed in 31 patients with suspected cerebral gliomas. PET and MRIs were co-registered and 52 ...


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