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Self-​assembling colloidal system for the ocular administration of cyclosporine A

Luschmann, Christoph, Tessmar, Joerg, Schoeberl, Simon, Strauss, O., Luschmann, Karl and Goepferich, Achim (2014) Self-​assembling colloidal system for the ocular administration of cyclosporine A. Cornea 33 (1), pp. 77-81.

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Abstract

PURPOSE: In this study, we developed a self-assembling micellar system to deliver cyclosporine A (CsA) in an aqueous solution to the cornea. METHODS: Two nonionic surfactants of the poly(ethylene glycol)-fatty alcohol ether type (Sympatens AS and Sympatens ACS) were characterized in terms of micelle size, shape, and charge, and their encapsulation efficiency for CsA. In an in situ single dose ...

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Item type:Article
Date:2014
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
ValueType
24162754PubMed ID
10.1097/ICO.0b013e3182a7f3bfDOI
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29289
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