Hegi, Monika E. 
; Diserens, Annie-Claire ; Gorlia, Thierry ; Hamou, Marie-France ; de Tribolet, Nicolas ; Weller, Michael ; Kros, Johan M. ; Hainfellner, Johannes A. ; Mason, Warren ; Mariani, Luigi ; Bromberg, Jacoline E. C. ; Hau, Peter ; Mirimanoff, René O. ; Cairncross, J. Gregory ; Janzer, Robert C. ; Stupp, Roger
; Diserens, Annie-Claire ; Gorlia, Thierry ; Hamou, Marie-France ; de Tribolet, Nicolas ; Weller, Michael ; Kros, Johan M. ; Hainfellner, Johannes A. ; Mason, Warren ; Mariani, Luigi ; Bromberg, Jacoline E. C. ; Hau, Peter ; Mirimanoff, René O. ; Cairncross, J. Gregory ; Janzer, Robert C. ; Stupp, Roger 
Zusammenfassung
BACKGROUND: Epigenetic silencing of the MGMT (O(sup 6)-methylguanine-DNA methyltransferase) DNA-repair gene by promoter methylation compromises DNA repair and has been associated with longer survival in patients with glioblastoma who receive alkylating agents. METHODS: We tested the relationship between MGMT silencing in the tumor and the survival of patients who were enrolled in a randomized ...
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