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TGF-beta in neural stem cells and in tumors of the central nervous system

Aigner, Ludwig ; Bogdahn, Ulrich



Abstract

Mechanisms that regulate neural stem cell activity in the adult brain are tightly coordinated. They provide new neurons and glia in regions associated with high cellular and functional plasticity, after injury, or during neurodegeneration. Because of the proliferative and plastic potential of neural stem cells, they are currently thought to escape their physiological control mechanisms and ...

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