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Maintenance therapy with 13-cis retinoid acid in high-grade glioma at complete response after first-line multimodal therapy--a phase-II study

Wismeth, Caecilia, Hau, Peter, Fabel, Klaus, Baumgart, Ulrike, Hirschmann, Birgit, Koch, Horst, Jauch, Tanja, Grauer, Oliver, Drechsel, Lisa, Brawanski, Alexander, Bogdahn, Ulrich and Steinbrecher, Andreas (2004) Maintenance therapy with 13-cis retinoid acid in high-grade glioma at complete response after first-line multimodal therapy--a phase-II study. Journal of neuro-oncology 68 (1), pp. 79-86.

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Abstract

There is an urgent need for strategies maintaining remission in patients with malignant glioma. Maintenance therapy with high-dose cRA is feasible and well tolerated over long periods of time. A controlled clinical trial to test the efficacy of cRA as a maintenance treatment in malignant glioma is warranted.


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Item type:Article
Date:2004
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
15174524PubMed ID
Classification:
NotationType
AdultMESH
Antineoplastic Agents/adverse effectsMESH
Brain Neoplasms/surgeryMESH
Combined Modality TherapyMESH
Disease ProgressionMESH
Feasibility StudiesMESH
FemaleMESH
Glioma/surgeryMESH
HumansMESH
Isotretinoin/therapeutic useMESH
MaleMESH
Middle AgedMESH
Neoplasm Recurrence, Local/etiologyMESH
Prospective StudiesMESH
Radiotherapy/adverse effectsMESH
Salvage TherapyMESH
Survival RateMESH
Treatment OutcomeMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29343
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