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Pegylated liposomal doxorubicin-efficacy in patients with recurrent high-grade glioma

Hau, Peter, Fabel, Klaus, Baumgart, Ulrike, Rümmele, Petra, Grauer, Oliver, Bock, Annekatrin, Dietmaier, Christopher, Dietmaier, Wolfgang, Dietrich, Jörg, Dudel, Christine, Hübner, Franz, Jauch, Tanya, Drechsel, Elisabeth, Kleiter, Ingo, Wismeth, Cäcile, Zellner, Anton, Brawanski, Alexander, Steinbrecher, Andreas, Marienhagen, Jörg and Bogdahn, Ulrich (2004) Pegylated liposomal doxorubicin-efficacy in patients with recurrent high-grade glioma. Cancer 100 (6), pp. 1199-1207.

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Abstract

Pegylated liposomal doxorubicin administered alone or in combination with tamoxifen is safe and moderately effective in patients with recurrent high-grade glioma. None of the putative predictors for response that were evaluated proved to be significant in this setting.


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Item type:Article
Date:2004
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
15022287PubMed ID
10.1002/cncr.20073DOI
Classification:
NotationType
AdultMESH
AgedMESH
Antineoplastic Agents/therapeutic useMESH
Antineoplastic Combined Chemotherapy Protocols/therapeutic useMESH
Brain Neoplasms/drug therapyMESH
Doxorubicin/therapeutic useMESH
Drug CarriersMESH
FemaleMESH
Glioma/drug therapyMESH
HumansMESH
ImmunohistochemistryMESH
MaleMESH
Middle AgedMESH
P-Glycoprotein/biosynthesisMESH
Peptides/therapeutic useMESH
Polyethylene Glycols/therapeutic useMESH
Quality of LifeMESH
Survival AnalysisMESH
Tamoxifen/therapeutic useMESH
Tomography, Emission-Computed, Single-PhotonMESH
Treatment OutcomeMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29344
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