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Pharmacokinetics of a Self-Microemulsifying Drug Delivery System of Tacrolimus

Suesskind-Schwendi, Marietta, Gruber, Michael, Touraud, Didier, Kunz, Werner, Schmid, Christof, Hirt, Stephan and Lehle, Karla (2013) Pharmacokinetics of a Self-Microemulsifying Drug Delivery System of Tacrolimus. Biomedicine & Pharmacotherapy 47 (6), pp. 469-473.

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Abstract

This study evaluated the pharmacokinetics of tacrolimus (Tac) in a novel self-microemulsifying drug delivery system (SMEDDS) for improved oral administration. SMEDDS Tac consisted of Et oleate as the oily phase, Solutol HS 15 as the surfactant and glycofurol as the co-surfactant and contained 0.5 mg/mL tacrolimus. Blood and tissue concns. of tacrolimus from two study groups (oral application of ...

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Item type:Article
Date:2013
Institutions:Chemistry and Pharmacy > Institut für Physikalische und Theoretische Chemie > Chair of Chemistry VI - Physical Chemistry (Solution Chemistry) > Prof. Dr. Werner Kunz
Identification Number:
ValueType
10.1016/j.biopha.2013.04.001DOI
Keywords:Prograf self microemulsifying drug delivery system pharmacokinetics
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29446
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