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Biodegradability and cytotoxicity on human cell lines of choline soaps: effects of chain length and cation

Klein, Regina ; Müller, Eva ; Kraus, Birgit ; Brunner, Gabi ; Estrine, Boris ; Touraud, Didier ; Heilmann, Jörg ; Kellermeier, Matthias ; Kunz, Werner


Using choline as a counterion in fatty acid surfactants substantially increases their H2O soly. as compared to classical Na and K soaps, and thereby enables the application of desirable longer-chain derivs. at ambient temp. Since choline can be decompd. both physiol. and environmentally, corresponding fatty acid soaps are considered to be highly biocompatible. Recent toxicity and ...


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