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Chromatin-Specific Regulation of Mammalian rDNA Transcription by Clustered TTF-I Binding Sites

Diermeier, Sarah, Nemmeth, Attila, Rehli, Michael, Grummt, Ingrid and Längst, Gernot (2013) Chromatin-Specific Regulation of Mammalian rDNA Transcription by Clustered TTF-I Binding Sites. PLoS Genetics 9.

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Date of publication of this fulltext: 12 Feb 2014 11:28

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Abstract

Enhancers and promoters often contain multiple binding sites for the same transcription factor, suggesting that homotypic clustering of binding sites may serve a role in transcription regulation. Here we show that clustering of binding sites for the transcription termination factor TTF-I downstream of the pre-rRNA coding region specifies transcription termination, increases the efficiency of ...

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Item type:Article
Date:12 September 2013
Institutions:Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III > Prof. Dr. Gernot Längst
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
10.1371/journal.pgen.1003786DOI
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:29515
Owner only: item control page

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