Direct cell-cell contact between Mesenchymal Stem Cells and Endothelial Progenitor Cells induces a Pericyte-like phenotype in vitro

URN to cite this document:: urn:nbn:de:bvb:355-epub-295425
DOI to cite this document:: 10.5283/epub.29542

Loibl, Markus ; Binder, Andreas ; Hermann, Marietta ; Duttenhoefer, Fabian ; Richards, Geoff R. ; Nerlich, Michael ; Alini, Mauro ; Verrier, Sophie

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Date of publication of this fulltext: 12 Feb 2014 12:59

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Abstract

Tissue engineering techniques for the regeneration of large bone defects require sufficient vascularisation of the applied constructs to ensure a sufficient supply of oxygen and nutrients. In our previous work, prevascularised 3D scaffolds have been successfully established by coculture of bone marrow derived stem cells (MSCs) and endothelial progenitor cells (EPCs). We identified stabilising ...