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The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis

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Dürr, Julius ; Lolas, Ihab B. ; Sørensen, Brian B. ; Schubert, Veit ; Houben, Andreas ; Melzer, Michael ; Deutzmann, Rainer ; Grasser, Marion ; Grasser, Klaus D.
License: Creative Commons: Attribution 3.0
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Date of publication of this fulltext: 18 Feb 2014 15:55


The heterodimeric complex SPT4/SPT5 is a transcript elongation factor (TEF) that directly interacts with RNA polymerase II (RNAPII) to regulate messenger RNA synthesis in the chromatin context. We provide biochemical evidence that in Arabidopsis, SPT4 occurs in a complex with SPT5, demonstrating that the SPT4/SPT5 complex is conserved in plants. Each subunit is encoded by two genes SPT4-1/2 and ...


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