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Dopamine and cognitive control: The influence of spontaneous eyeblink rate, DRD4 exon III polymorphism and gender on flexibility in set-shifting

Müller, Johannes ; Dreisbach, Gesine ; Brocke, Burkhard ; Lesch, Klaus-Peter ; Strobel, Alexander ; Goschke, Thomas



Abstract

Converging evidence suggests a modulatory role of dopamine in cognitive control. We investigated the influence of two correlates of dopaminergic activity, the spontaneous eyeblink rate and the DRD4 exon III polymorphism, and the potential impact of gender on flexibility in an attentional set-shifting paradigm. The objective of the study was to confirm previous findings of an association between ...

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