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Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain

Proescholdt, M. A., Heiss, J. D., Walbridge, S., Mühlhauser, J., Capogrossi, M. C., Oldfield, E. H. and Merrill, M. J. (1999) Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brain. Journal of neuropathology and experimental neurology 58 (6), pp. 613-627.

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Abstract

Vascular endothelial growth factor (VEGF) is an angiogenic growth factor that also induces vascular permeability and macrophage migration. VEGF expression is weak in normal adult brain, but is strongly upregulated in glioma cells and reactive astrocytes, suggesting that chronic overexpression of VEGF in the brain contributes to blood-brain barrier (BBB) breakdown. We examined the effects of ...

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Item type:Article
Date:1999
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29700
Owner only: item control page
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