Go to content
UR Home

A Novel Antibody against Human Properdin Inhibits the Alternative Complement System and Specifically Detects Properdin from Blood Samples

URN to cite this document:
DOI to cite this document:
Pauly, Diana ; Nagel, Benedikt M. ; Reinders, Jörg ; Killian, Tobias ; Wulf, Matthias ; Ackermann, Susanne ; Ehrenstein, Boris ; Zipfel, Peter F. ; Skerka, Christine ; Weber, Bernhard H. F.
License: Creative Commons: Attribution 3.0
PDF - Published Version
Date of publication of this fulltext: 19 May 2014 07:51


The complement system is an essential part of the innate immune system by acting as a first line of defense which is stabilized by properdin, the sole known positive regulator of the alternative complement pathway. Dysregulation of complement can promote a diversity of human inflammatory diseases which are treated by complement inhibitors. Here, we generated a novel blocking monoclonal antibody ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons