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Synthesis of Phenyl-1-benzoxepinols Isolated from Butcher’s Broom and Analogous Benzoxepines

Herrmann, Josef M., Untergehrer, Monika, Jürgenliemk, Guido, Heilmann, Jörg and König, Burkhard (2014) Synthesis of Phenyl-1-benzoxepinols Isolated from Butcher’s Broom and Analogous Benzoxepines. European Journal of Organic Chemistry 2014 (15), pp. 3170-3181.

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Extracts of Ruscus aculeatus L., known as butcher's broom, are mainly used for the treatment of chronic venous insufficiency (CVI). In a recent study on the phenolic compounds of Rusci rhizoma, new phenyl-1-benzoxepinols were isolated. As the therapeutic effect of butcher's broom is ascribed to the pharmacological activity of the main constituents, steroidal saponins and their aglycones the ...


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Item type:Article
Date:May 2014
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
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Keywords:Natural products / Oxygen heterocycles / Acylation / Antioxidants
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30090
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