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Distinct metabolic differences between various human cancer and primary cells

Dettmer, Katja ; Vogl, Franziska C. ; Ritter, Axel P. ; Zhu, Wentao ; Nürnberger, Nadine ; Kreutz, Marina ; Oefner, Peter J. ; Gronwald, Wolfram ; Gottfried, Eva



Abstract

Recent years have seen resurging interest in cancer cell metabolism and the role of secreted cancer metabolites in modulating the tumor stroma. Using a combination of nontargeted and targeted LC and GC-MS methods, the exometabolomes of three leukemia, two melanoma, three renal cell carcinoma, two colorectal adenocarcinoma, four hepatocellular carcinoma, three breast cancer, two bladder carcinoma, ...

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