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Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens.

Masqué-Soler, Neus, Szczepanowski, Monika, Kohler, Christian, Spang, Rainer and Klapper, Wolfram (2013) Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens. Blood 122 (11), pp. 1985-1986.

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Abstract

The most frequent mature aggressive B-cell lymphomas are diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL). Patients suffering from molecularly defined BL (mBL) but treated with a regimen developed for DLBCL show an unfavorable outcome compared with mBL treated with chemotherapy regimens for BL. Distinguishing BL from DLBCL by conventional histopathology is challenging in lymphomas ...

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Item type:Article
Date:12 September 2013
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number:
ValueType
24030260PubMed ID
10.1182/blood-2013-06-508937DOI
Classification:
NotationType
B-Lymphocytes/pathologyMESH
BiopsyMESH
FormaldehydeMESH
Gene Expression Profiling/methodsMESH
Gene Expression Regulation, NeoplasticMESH
HumansMESH
Linear ModelsMESH
Lymphoma, B-Cell/pathologyMESH
Paraffin EmbeddingMESH
Reproducibility of ResultsMESH
Tissue FixationMESH
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:30528
Owner only: item control page

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