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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-305678
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.30567
Zusammenfassung
To study expression and function of methylthioadenosine phosphorylase (MTAP), the rate-limiting enzyme in the methionine and adenine salvage pathway, in chronic liver disease. DESIGN: MTAP expression was analyzed by qRT-PCR, Western blot and immunohistochemical analysis. Levels of MTA were determined by liquid chrmatography-tandem mass spectrometry. RESULTS: MTAP was downregulated in hepatocytes ...
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