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Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells

Hertwig, Falk, Meyer, Katharina, Braun, Sebastian, Ek, Sara, Spang, Rainer, Pfenninger, Cosima V., Artner, Isabella, Prost, Gaëlle, Chen, Xinbin, Biegel, Jaclyn A., Judkins, Alexander R., Englund, Elisabet and Nuber, Ulrike A. (2012) Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells. Cancer research 72 (13), pp. 3381-3392.

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Abstract

Although brain tumors are classified and treated based upon their histology, the molecular factors involved in the development of various tumor types remain unknown. In this study, we show that the type and order of genetic events directs the development of gliomas, central nervous system primitive neuroectodermal tumors, and atypical teratoid/rhabdoid-like tumors from postnatal mouse neural ...

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Item type:Article
Date:July 2012
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number:
ValueType
22719073PubMed ID
10.1158/0008-5472.CAN-11-3525DOI
Classification:
NotationType
AnimalsMESH
Brain Neoplasms/pathologyMESH
Cell LineageMESH
Chromatin Assembly and DisassemblyMESH
Flow CytometryMESH
MiceMESH
Mice, Inbred C57BLMESH
Mice, KnockoutMESH
Neural Stem Cells/cytologyMESH
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:30586
Owner only: item control page
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