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Comprehensive two-dimensional gas chromatography in metabolomics

Almstetter, Martin F. ; Oefner, Peter J. ; Dettmer, Katja



Abstract

One of the major objectives in metabolomics is the identification of subtle changes in metabolite profiles as affected by genetic or environmental factors. Comprehensive two-dimensional gas chromatography (GC × GC) hyphenated to a fast-acquisition mass spectrometer is a well-established analytical technique to study the composition of complex samples due to its enhanced separation capacity, ...

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