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Performance evaluation of gas chromatography-atmospheric pressure chemical ionization-time-of-flight mass spectrometry for metabolic fingerprinting and profiling

Wachsmuth, Christian, Almstetter, Martin F., Waldhier, Magdalena Ch., Gruber, Michael, Nürnberger, Nadine, Oefner, Peter J. and Dettmer, Katja (2011) Performance evaluation of gas chromatography-atmospheric pressure chemical ionization-time-of-flight mass spectrometry for metabolic fingerprinting and profiling. Analytical chemistry 83 (19), pp. 7514-7322.

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Abstract

Gas chromatography-atmospheric-pressure chemical ionization-time-of-flight mass spectrometry (GC-APCI-TOFMS) was compared to GC × GC-electron ionization (EI)-TOFMS, GC-EI-TOFMS, GC-chemical ionization (CI)-quadrupole mass spectrometry (qMS), and GC-EI-qMS in terms of reproducibility, dynamic range, limit of detection, and quantification using a mix of 43 metabolites and 12 stable isotope-labeled ...

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Item type:Article
Date:October 2011
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
Identification Number:
ValueType
21859117PubMed ID
10.1021/ac201719dDOI
Classification:
NotationType
Atmospheric PressureMESH
Chromatography, GasMESH
Escherichia coli/metabolismMESH
Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationMESH
Dewey Decimal Classification:500 Science > 500 Natural sciences & mathematics
500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30626
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