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Advances in amino acid analysis

Kaspar, Hannelore ; Dettmer, Katja ; Gronwald, Wolfram ; Oefner, Peter J.


Amino acids are important targets for metabolic profiling. For decades, amino acid analysis has been accomplished by either cation-exchange or reversed-phase liquid chromatography coupled to UV absorbance or fluorescence detection of pre-column or post-column-derivatized amino acids. Recent years have seen great progress in the development of direct-infusion or hyphenated mass spectrometry in the ...


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