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Capillary electrophoresis and column chromatography in biomedical chiral amino acid analysis

Waldhier, Magdalena Ch. ; Gruber, Michael ; Dettmer, Katja ; Oefner, Peter J.



Abstract

Free amino acids are typically quantified as the sum of their enantiomers, because in terrestrial organisms they mainly exist in the left-handed form. However, with increasing understanding of the biological significance of right-handed amino acids interest in enantioselective quantification of amino acids has steadily increased. Initially, electrophoretic and chromatographic methods using chiral ...

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