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Protein-Protein Interaction Analysis by Docking

URN to cite this document:
urn:nbn:de:bvb:355-epub-306731
Fink, Florian ; Ederer, Stephan ; Gronwald, Wolfram
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Date of publication of this fulltext: 20 Aug 2014 08:06


Abstract

Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach.


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