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Protein-Protein Interaction Analysis by Docking

Fink, Florian, Ederer, Stephan and Gronwald, Wolfram (2009) Protein-Protein Interaction Analysis by Docking. Algorithms 2 (1), pp. 429-436.

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Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach.

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Item type:Article
Date:10 March 2009
Institutions:Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Funktionelle Genomik (Prof. Oefner)
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Keywords:protein-protein docking; verification of protein interactions; 3D protein structures
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30673
Owner only: item control page


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