Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia

Rhein, P., Scheid, S., Ratei, R., Hagemeier, C., Seeger, K., Kirschner-Schwabe, R., Moericke, A., Schrappe, M., Spang, Rainer, Ludwig, W.-D. and Karawajew, L. (2007) Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia. Leukemia 21 (5), pp. 897-905.

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Involved Institutions

• Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang) Informatics and Data Science > Department Computational Life Science > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)

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Details

Item type	Article
Journal or Publication Title	Leukemia
Publisher:	Nature Publishing Group
Volume:	21
Number of Issue or Book Chapter:	5
Page Range:	pp. 897-905
Date	May 2007
Institutions	Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang) Informatics and Data Science > Department Computational Life Science > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Identification Number	Value Type 17330098 PubMed ID 10.1038/sj.leu.2404613 DOI
Classification	Notation Type Adolescent MESH Antigens, CD11b/analysis MESH B-Lymphocytes/metabolism MESH Blast Crisis/metabolism MESH Cell Cycle MESH Cell Proliferation MESH Child MESH Child, Preschool MESH Female MESH Gene Expression Profiling MESH Humans MESH Infant MESH Male MESH Methotrexate/therapeutic use MESH Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology MESH Prednisone/therapeutic use MESH Receptors, Interferon/analysis MESH
Dewey Decimal Classification	500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine
Status	Published
Refereed	Yes, this version has been refereed
Created at the University of Regensburg	No
Item ID	30689

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