Go to content
UR Home

Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation

Hennig, Robert, Pollinger, Klaus, Veser, Anika, Breunig, Miriam and Goepferich, Achim (2014) Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation. Journal of Controlled Release 194, pp. 20-27.

Full text not available from this repository.

at publisher (via DOI)


The conjugation of receptor ligands to shielded nanoparticles is a widely used strategy to precisely control nanoparticle–cell interactions. However, it is often overlooked that a ligand's affinity can be severely impaired by its attachment to the polyethylene glycol (PEG) chains that are frequently used to protect colloids from serum protein adsorption. Using the model ligand EXP3174, a ...


Export bibliographical data

Item type:Article
Date:August 2014
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
Keywords:Small molecules; PEGylation; Nanoparticles; Multivalency; Quantum dots; Active targeting
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:30699
Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons