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Synthesis of natural and non-natural diarylheptanoids and evaluation of their neuroprotective activity

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Jirásek, Petr
Date of publication of this fulltext: 04 Aug 2015 16:18

Abstract (English)

Diarylheptanoids are natural products consisting of two aromatic rings connected by a seven carbon aliphatic chain which can be found in certain parts of various trees and shrubs as well as in rhizomes of some medicinal herbs. The most prominent representative of the diarylheptanoid class is curcumin (1), a linear diferuloyl methane from Curcuma longa L. with a broad spectrum of pharmacological ...


Translation of the abstract (German)

Diarylheptanoide sind Naturstoffe mit zwei Arylringen, die durch eine aliphatische Kette aus sieben Kohlenstoffen verknüpft sind. Sie wurden in verschiedenen Teilen bestimmter Bäume und Sträucher entdeckt, ebenso in Rhizomen mancher Heilpflanzen. Der bekannteste Vertreter der Diarylheptanoide ist Curcumin (1), ein Diferuloylmethan aus Curcuma longa L. mit einem breiten Spektrum an ...


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