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Studies on the assembly process of large subunit ribosomal proteins in S.cerevisiae

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Ohmayer, Uli
Date of publication of this fulltext: 01 Oct 2015 16:09

Abstract (English)

Ribosomes are ribonucleoprotein (RNP) particles that catalyze the translation of the genetic information of messenger RNA (mRNA) into proteins. The biogenesis of eukaryotic ribosomes is a highly complex process that starts in the nucleolus where the ribosomal RNA (rRNA) is synthesized by RNA Polymerases I and III. Three of the four rRNA molecules are produced as one precursor molecule (pre-rRNA) ...


Translation of the abstract (German)

Ribosomen sind Ribonucleoprotein (RNP) Partikel, die für die Translation der in mRNA enthaltenen genetischen Information in Proteine verantwortlich sind, indem sie die Verknüpfung der einzelnen Aminosäuren zu Proteinen katalysieren. Ihre Biogenese ist in eukaryotischen Organismen ein sehr komplexer Vorgang welcher im Nucleolus beginnt und im Zytoplasma endet. Ribosomale RNA (rRNA) wird in der ...


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