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Controlled release of therapeutic antibody formats

Schweizer, Daniel ; Serno, Tim ; Goepferich, Achim



Abstract

The local administration of antibodies can represent in many cases a significant improvement for antibody-based therapies. The benefits of local delivery include high drug concentrations at the target site, the possibility of lower drug dosing and less systemic drug exposure. Currently, the most relevant delivery sites for therapeutic antibodies are the posterior segments of the eye, mucosal ...

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