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Controlled release of therapeutic antibody formats

Schweizer, Daniel, Serno, Tim and Goepferich, Achim (2014) Controlled release of therapeutic antibody formats. European Journal of Pharmaceutics and Biopharmaceutics 88 (2), pp. 291-309.

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Abstract

The local administration of antibodies can represent in many cases a significant improvement for antibody-based therapies. The benefits of local delivery include high drug concentrations at the target site, the possibility of lower drug dosing and less systemic drug exposure. Currently, the most relevant delivery sites for therapeutic antibodies are the posterior segments of the eye, mucosal ...

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Item type:Article
Date:2014
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Identification Number:
ValueType
10.1016/j.ejpb.2014.08.001DOI
Keywords:Ocular antibody delivery; Biologic; Formulation, Protein; Antibody therapy; Sustained release; Local delivery; Drug delivery system; Therapeutic antibodies;Polymers
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:31024
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