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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-313608
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.31360
Zusammenfassung
Mutations in the oncogenic PIK3CA gene are found in 10–20% of colorectal cancers (CRCs) and are associated with poor prognosis. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and agonistic TRAIL death receptor antibodies emerged as promising anti-neoplastic therapeutics, but to date failed to prove their capability in the clinical setting as especially primary tumors exhibit high ...
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