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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-315056
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.31505
Zusammenfassung
Signal transducer and activator of transcription STAT5 is essential for the regulation of proliferation and survival genes. Its activity is tightly regulated through cytokine signaling and is often upregulated in cancer. We showed previously that the deacetylase inhibitor trichostatin A (TSA) inhibits STAT5-mediated transcription by preventing recruitment of the transcriptional machinery at a ...
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